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Product name:Boswellia Serrata Extract

English name:Boswelia Serrata Extract

Spec.:Boswelia Serrata Extract

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Product description


Quick Details  
Model NO.: STH014
CAS NO.: 631-69-6
Formula: C30H48O3
Certification: SGS
Application Dietary supplement, Medicine,body build
Application Form Tablet, Capsule
Appearance Off-white powder
Assay Method: HPLC
Specification: 65%β-Boswellic Acid
Transport Package 25kg/Drum
Origin: China
H.S. Code  
Description:
β-Boswellic Acid,FRANKINIC ACID Anticancer
  • Chemical Properties β-Boswellic is Off-White Solid
  • Uses The principal constitutents of frankincense (olibanum). A specific, nonredox inhibitor of 5-lipoxygenase used to treat inflammation.
  • Anticancer Research It is a natural pentacyclic triterpenediol and occurs in Boswellia serrata plants as anisomeric blend of 3α, 24-dihydroxyolean-12-ene and 3α, 24-dihydroxyurs-12-ene.It induces apoptosis in various cancer cells. The events involved in this process areexcessive reactive oxygen species (ROS), nitric oxide (NO) formation, DNA ladderformation, and increased sub-G0 phase in cell cycle. This ultimately results incleavage of Bcl-2 and translocation of Bax to mitochondria, which lead to the lossof mitochondrial potential and release of cyt-c and other factors into cytosol. All these events are linked with reduced expression of survivin and inhibitor of caspase-activatedDNases (ICAD) that leads to the activation of poly(ADP-ribose) polymerase(PARP). The triterpene upregulates the expression of cell death receptor-4(DR-4) and tumor necrosis factor receptor-1 (TNF-R1), where both lead to activationof caspase-8 (Huang et al. 2000; Desai et al. 2008; Lu et al. 2008).

Product specification

 

 

 

ITEM

SPECIFICATION

RESULTS

PHYSICAL CONTROL

ASSAY ( TITRATION)

Boswellic Acid≥65.0%

65.50%

Appearance

White Fine Powder

Complies

Odor

Characteristic

Complies

Sulphated Ash

≤5.0%

3.36%

Loss on drying

≤5.0%

3.09%

Sieve Analysis

100% pass 80 mesh

Complies

CHEMICAL CONTROL

Heavy Metals                        

≤10ppm

Complies

Arsenic

≤2 ppm

Complies

MICROBIOLOGY CONTROL

Total Plate Count

≤10000 cfu/g

Complies

Yeast & Mold

≤100 cfu/g

Complies

E.Coli  

Negative

Complies

Salmonella

Negative

Complies


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